Pittman was born in Mississippi and raised in Nashville, Tennessee. She received her Bachelor of Science in Voice and Opera at Northwestern University and a Masters of Fine Arts from NYU's Graduate Acting Program.
Pittman began her acting career in 2009, starting off with numerous guest starring roles in television series such as 30 Rock, Law & Order, Law & Order: Special Victims Unit, The Good Wife, and House of Cards. She is perhaps best known for her roles in FX's Emmy nominated The Americans and Netflix's Screen Actors Guild nominated Marvel series Luke Cage. Along with acting in television and film, Pittman also partakes in Broadway. She starred in the Tony nominated Broadway play Disgraced.